Avoid distractions when you are driving. This includes those in the car, such as the radio or your cellphone, as well as those outside the car. It's best to keep your eyes on the road at all times.
Don't drive when you are impaired. This not only includes the obvious situation of having had too much to drink, but it also includes things such as avoiding driving when you are tired or if you are having emotional problems.
Keep your car in good shape. Keeping your tires properly inflated and making sure your headlights and taillights work are important to keep you and others safe on the road.